Merkel, Olivia: search on Z-Library

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1

Targeting KRAS Mutant Lung Cancer Cells with siRNA-Loaded Bovine Serum Albumin Nanoparticles

Mehta, Aditi, Dalle Vedove, Elena, Isert, Lorenz, Merkel, Olivia M.

Journal:

Pharmaceutical Research

Year:

2019

Language:

english

File:

PDF, 3.38 MB

english, 2019

2

Applications of polymer micelles for imaging and drug delivery

Movassaghian, Sara, Merkel, Olivia M., Torchilin, Vladimir P.

Journal:

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

Year:

2015

Language:

english

File:

PDF, 1011 KB

english, 2015

3

Mannose and Mannose-6-Phosphate Receptor-Targeted Drug Delivery Systems and Their Application in Cancer Therapy

Dalle Vedove, Elena, Costabile, Gabriella, Merkel, Olivia M.

Journal:

Advanced Healthcare Materials

Year:

2018

Language:

english

File:

PDF, 1.45 MB

english, 2018

4

Correlating quantitative tumor accumulation and gene knockdown using SPECT/CT and bioluminescence imaging within an orthotopic ovarian cancer model

Jones, Steven K., Douglas, Kirk, Shields, Anthony F., Merkel, Olivia M.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.25 MB

english, 2018

5

Nose-to-brain delivery of biologics

Schwarz, Bettina, Merkel, Olivia M

Journal:

Therapeutic Delivery

Year:

2019

Language:

english

File:

PDF, 421 KB

english, 2019

6

CRISPR-cas gene-editing as plausible treatment of neuromuscular and nucleotide-repeat-expansion diseases: A systematic review

Babačić, Haris, Mehta, Aditi, Merkel, Olivia, Schoser, Benedikt, Lewin, Alfred S.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.99 MB

english, 2019

7

Cover Image, Volume 12, Issue 5

Keil, Tobias W. M., Baldassi, Domizia, Merkel, Olivia M.

Journal:

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

Year:

2020

File:

PDF, 12.21 MB

2020

8

Targeted delivery of siRNA to activated T Cells via transferrin-polyethylenimine (Tf-PEI) as a potential therapy of asthma

Xie, Yuran, Kim, Na Hyung, Nadithe, Venkatareddy, Schalk, Dana, Thakur, Archana, Kılıç, Ayşe, Lum, Lawrence G., Bassett, David J.P., Merkel, Olivia M.

Journal:

Journal of Controlled Release

Year:

2016

Language:

english

File:

PDF, 1003 KB

english, 2016

9

Targeted Delivery of siRNA to Transferrin Receptor Overexpressing Tumor Cells via Peptide Modified Polyethylenimine

Xie, Yuran, Killinger, Bryan, Moszczynska, Anna, Merkel, Olivia

Journal:

Year:

2016

Language:

english

File:

PDF, 2.75 MB

english, 2016

10

Advances and Challenges in the Delivery of Nucleic Acid Therapeutics (Volume 2) || Inhaled delivery of siRNA

Year:

2015

File:

PDF, 2.97 MB

2015

11

Biodegradable Poly(ethylene carbonate) Nanoparticles as a Promising Drug Delivery System with “Stealth” Potential

Nadja Bege, Thomas Renette, Mirko Jansch, Regina Reul, Olivia Merkel, Holger Petersen, Catherine Curdy, Rainer H. Müller, Thomas Kissel

Journal:

Macromolecular Bioscience

Year:

2011

Language:

english

File:

PDF, 493 KB

english, 2011

12

A new synthesis method and degradation of hyper-branched polyethylenimine grafted polycaprolactone block mono-methoxyl poly (ethylene glycol) copolymers (hy-PEI-g-PCL-b-mPEG) as potential DNA delivery vectors

Yu Liu, Juliane Nguyen, Terry Steele, Olivia Merkel, Thomas Kissel

Journal:

Year:

2009

Language:

english

File:

PDF, 714 KB

english, 2009

13

Integrin α ν β 3 Targeted Gene Delivery Using RGD Peptidomimetic Conjugates with Copolymers of PEGylated Poly(ethylene imine)

Merkel, Olivia M., Germershaus, Oliver, Wada, Carol K., Tarcha, Peter J., Merdan, Thomas, Kissel, Thomas

Journal:

Bioconjugate Chemistry

Year:

2009

Language:

english

File:

PDF, 3.16 MB

english, 2009

14

Biophysical characterization of hyper-branched polyethylenimine-graft- polycaprolactone-block-mono-methoxyl-poly(ethylene glycol) copolymers (hy-PEI-PCL-mPEG) for siRNA delivery

Yu Liu, Olga Samsonova, Brian Sproat, Olivia Merkel, Thomas Kissel

Journal:

Journal of Controlled Release

Year:

2011

Language:

english

File:

PDF, 1.02 MB

english, 2011

15

Nanoimprinting of topographical and 3D cell culture scaffolds

Elsayed, Maha, Merkel, Olivia M

Journal:

Year:

2014

Language:

english

File:

PDF, 1.49 MB

english, 2014

16

Perfectly shaped siRNA delivery

Merkel, Olivia M, Mintzer, Meredith A, Simanek, Eric E, Kissel, Thomas

Journal:

Therapeutic Delivery

Year:

2010

Language:

english

File:

PDF, 1.32 MB

english, 2010

17

Evaluation of β-Sitosterol Loaded PLGA and PEG-PLA Nanoparticles for Effective Treatment of Breast Cancer: Preparation, Physicochemical Characterization, and Antitumor Activity

Andima, Moses, Costabile, Gabriella, Isert, Lorenz, Ndakala, Albert, Derese, Solomon, Merkel, Olivia

Journal:

Year:

2018

Language:

english

File:

PDF, 3.59 MB

english, 2018

18

Enhancing in vivo circulation and siRNA delivery with biodegradable polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol) copolymers

Mengyao Zheng, Damiano Librizzi, Ayşe Kılıç, Yu Liu, Harald Renz, Olivia M. Merkel, Thomas Kissel

Journal:

Year:

2012

Language:

english

File:

PDF, 1.18 MB

english, 2012

19

Amphiphilic and biodegradable hy-PEI-g-PCL-b-PEG copolymers efficiently mediate transgene expression depending on their graft density

Mengyao Zheng, Yu Liu, Olga Samsonova, Thomas Endres, Olivia Merkel, Thomas Kissel

Journal:

International Journal of Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 1.60 MB

english, 2012

20

Influence of Polyethylene Glycol Chain Length on the Physicochemical and Biological Properties of Poly(ethylene imine)- graft -Poly(ethylene glycol) Block Copolymer/SiRNA Polyplexes

Mao, Shirui, Neu, Michael, Germershaus, Oliver, Merkel, Olivia, Sitterberg, Johannes, Bakowsky, Udo, Kissel, Thomas

Journal:

Bioconjugate Chemistry

Year:

2006

Language:

english

File:

PDF, 393 KB

english, 2006

21

siRNA Delivery to the lung: What's new?

Merkel, Olivia M., Rubinstein, Israel, Kissel, Thomas

Journal:

Advanced Drug Delivery Reviews

Year:

2014

Language:

english

File:

PDF, 1.44 MB

english, 2014

22

Revisiting the value of competition assays in folate receptor-mediated drug delivery

Jones, Steven K., Sarkar, Anwesha, Feldmann, Daniel P., Hoffmann, Peter, Merkel, Olivia M.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.43 MB

english, 2017

23

In vitro and in vivo delivery of siRNA via VIPER polymer system to lung cells

Feldmann, Daniel P., Cheng, Yilong, Kandil, Rima, Xie, Yuran, Mohammadi, Mariam, Harz, Hartmann, Sharma, Akhil, Peeler, David J., Moszczynska, Anna, Leonhardt, Heinrich, Pun, Suzie H., Merkel, Olivia

Journal:

Journal of Controlled Release

Year:

2018

Language:

english

File:

PDF, 1.32 MB

english, 2018

24

In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(–PEG)/siRNA complexes

Anastasia Malek, Olivia Merkel, Ludger Fink, Frank Czubayko, Thomas Kissel, Achim Aigner

Journal:

Toxicology and Applied Pharmacology

Year:

2009

Language:

english

File:

PDF, 860 KB

english, 2009

25

The advantages of pulmonary delivery of therapeutic siRNA

Feldmann, Daniel P, Merkel, Olivia M

Journal:

Therapeutic Delivery

Year:

2015

Language:

english

File:

PDF, 1.29 MB

english, 2015

26

Folate Receptor Targeted Delivery of siRNA and Paclitaxel to Ovarian Cancer Cells via Folate Conjugated Triblock Co-polymer to Overcome TLR4 Driven Chemotherapy Resistance

Jones, Steven Kevin, Lizzio, Vincent, Merkel, Olivia

Journal:

Biomacromolecules

Year:

2015

Language:

english

File:

PDF, 2.09 MB

english, 2015

27

Lipids and polymers in pharmaceutical technology: lifelong companions

Siepmann, Juergen, Faham, Amina, Clas, Sophie-Dorothée, Boyd, Ben J., Jannin, Vincent, Bernkop-Schnürch, Andreas, Zhao, Hang, Lecommandoux, Sébastien, Evans, James C., Allen, Christine, Merkel, Olivia

Journal:

International Journal of Pharmaceutics

Year:

2019

Language:

english

File:

PDF, 1.70 MB

english, 2019

28

From Adsorption to Covalent Bonding: Apolipoprotein E Functionalization of Polymeric Nanoparticles for Drug Delivery Across the BloodâBrain Barrier

Hartl, Natascha, Adams, Friederike, Merkel, Olivia M.

Journal:

Advanced Therapeutics

Year:

2020

File:

PDF, 2.08 MB

2020

29

In vitro and in vivo complement activation and related anaphylactic effects associated with polyethylenimine and polyethylenimine-graft-poly(ethylene glycol) block copolymers

Olivia M. Merkel, Rudolf Urbanics, Peter Bedőcs, Zoltán Rozsnyay, László Rosivall, Miklós Toth, Thomas Kissel, Janos Szebeni

Journal:

Year:

2011

Language:

english

File:

PDF, 808 KB

english, 2011

30

[Handbook of Experimental Pharmacology] || Flow Cytometry-Based Cell Type-Specific Assessment of Target Regulation by Pulmonary siRNA Delivery

Merkel, Olivia M.

Year:

2018

File:

PDF, 349 KB

2018

31

Screening Nylon-3 Polymers, a New Class of Cationic Amphiphiles, for siRNA Delivery

Nadithe, Venkatareddy, Liu, Runhui, Killinger, Bryan A., Movassaghian, Sara, Kim, Na Hyung, Moszczynska, Anna B., Masters, Kristyn S., Gellman, Samuel H., Merkel, Olivia M.

Journal:

Molecular Pharmaceutics

Year:

2015

Language:

english

File:

PDF, 2.85 MB

english, 2015

32

Polymer-related off-target effects in non-viral siRNA delivery

Olivia M. Merkel, Andrea Beyerle, Benedikt M. Beckmann, Mengyao Zheng, Roland K. Hartmann, Tobias Stöger, Thomas H. Kissel

Journal:

Year:

2011

Language:

english

File:

PDF, 1.74 MB

english, 2011

33

Nonviral Pulmonary Delivery of siRNA

Merkel, Olivia M., Kissel, Thomas

Journal:

Accounts of Chemical Research

Year:

2012

Language:

english

File:

PDF, 2.57 MB

english, 2012

34

Fast degrading polyesters as siRNA nano-carriers for pulmonary gene therapy

Juliane Nguyen, Terry W.J. Steele, Olivia Merkel, Regina Reul, Thomas Kissel

Journal:

Journal of Controlled Release

Year:

2008

Language:

english

File:

PDF, 859 KB

english, 2008

35

Nonviral siRNA Delivery to the Lung: Investigation of PEG−PEI Polyplexes and Their In Vivo Performance

Merkel, Olivia M., Beyerle, Andrea, Librizzi, Damiano, Pfestroff, Andreas, Behr, Thomas M., Sproat, Brian, Barth, Peter J., Kissel, Thomas

Journal:

Molecular Pharmaceutics

Year:

2009

Language:

english

File:

PDF, 3.82 MB

english, 2009

36

Targeted Drug Delivery: Mannose and Mannose-6-Phosphate Receptor-Targeted Drug Delivery Systems and Their Application in Cancer Therapy (Adv. Healthcare Mater. 14/2018)

Dalle Vedove, Elena, Costabile, Gabriella, Merkel, Olivia M.

Journal:

Advanced Healthcare Materials

Year:

2018

File:

PDF, 3.29 MB

2018

37

Controlled pulmonary drug and gene delivery using polymeric nano-carriers

Moritz Beck-Broichsitter, Olivia M. Merkel, Thomas Kissel

Journal:

Journal of Controlled Release

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

38

Influence of Oligospermines Architecture on Their Suitability for siRNA Delivery

Elsayed, Maha, Corrand, Vincent, Kolhatkar, Vidula, Xie, Yuran, Kim, Na Hyung, Kolhatkar, Rohit, Merkel, Olivia M.

Journal:

Biomacromolecules

Year:

2014

Language:

english

File:

PDF, 3.76 MB

english, 2014

39

Physicochemical and In Vitro Evaluation of Drug Delivery of an Antibacterial Synthetic Benzophenone in Biodegradable PLGA Nanoparticles

Costabile, Gabriella, Gasteyer, Kathrin I., Nadithe, Venkatereddy, Van Denburgh, Katherine, Lin, Qian, Sharma, Shiv, Reineke, Joshua J., Firestine, Steven M., Merkel, Olivia M.

Journal:

AAPS PharmSciTech

Year:

2018

Language:

english

File:

PDF, 1.37 MB

english, 2018

40

Immunogenicity of Cas9 Protein

Mehta, Aditi, Merkel, Olivia M.

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 562 KB

english, 2019

41

Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: Effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging

Olivia M. Merkel, Damiano Librizzi, Andreas Pfestroff, Tino Schurrat, Kevin Buyens, Niek N. Sanders, Stefaan C. De Smedt, Martin Béhé, Thomas Kissel

Journal:

Journal of Controlled Release

Year:

2009

Language:

english

File:

PDF, 1.47 MB

english, 2009

42

Polycationic triazine-based dendrimers: effect of peripheral groups on transfection efficiency

Mintzer, Meredith A., Merkel, Olivia M., Kissel, Thomas, Simanek, Eric E.

Journal:

New Journal of Chemistry

Year:

2009

Language:

english

File:

PDF, 702 KB

english, 2009

43

Pulmonary Gene Delivery Using Polymeric Nonviral Vectors

Merkel, Olivia M., Zheng, Mengyao, Debus, Heiko, Kissel, Thomas

Journal:

Bioconjugate Chemistry

Year:

2012

Language:

english

File:

PDF, 1.58 MB

english, 2012

44

Characterization of Dopaminergic System in the Striatum of Young Adult Park2−/− Knockout Rats

Gemechu, Jickssa M., Sharma, Akhil, Yu, Dongyue, Xie, Yuran, Merkel, Olivia M., Moszczynska, Anna

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.08 MB

english, 2018

45

T-cell targeted pulmonary siRNA delivery for the treatment of asthma

Keil, Tobias W. M., Baldassi, Domizia, Merkel, Olivia M.

Journal:

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

Year:

2020

File:

PDF, 1.89 MB

2020

46

Nanoparticle-Mediated Gene Silencing for Sensitization of Lung Cancer to Cisplatin Therapy

Feldmann, Daniel P., Heyza, Joshua, Zimmermann, Christoph M., Patrick, Steve M., Merkel, Olivia M.

Journal:

Year:

2020

File:

PDF, 919 KB

2020

47

Advances and Challenges in the Delivery of Nucleic Acid Therapeutics (Volume 1) || Natural cationic polymers for gene delivery

Merkel, Olivia, Amiji, Mansoor

Year:

2015

Language:

english

File:

PDF, 3.49 MB

english, 2015

48

Characterization of spray dried powders with nucleic acid-containing PEI nanoparticles

Keil, Tobias W.M., Feldmann, Daniel P, Costabile, Gabriella, Zhong, Qian, da Rocha, Sandro, Merkel, Olivia M

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2019

Language:

english

File:

PDF, 3.19 MB

english, 2019

49

Molecular modeling and in vivo imaging can identify successful flexible triazine dendrimer-based siRNA delivery systems

Olivia M. Merkel, Mengyao Zheng, Meredith A. Mintzer, Giovanni M. Pavan, Damiano Librizzi, Marek Maly, Helmut Höffken, Andrea Danani, Eric E. Simanek, Thomas Kissel

Journal:

Journal of Controlled Release

Year:

2011

Language:

english

File:

PDF, 1.46 MB

english, 2011

50

Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice

Andrea Beyerle, Andrea Braun, Olivia Merkel, Felix Koch, Thomas Kissel, Tobias Stoeger

Journal:

Journal of Controlled Release

Year:

2011

Language:

english

File:

PDF, 452 KB

english, 2011

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